Exploring the intersection of epigenetics, DNA repair, and immunology from studies of ICF syndrome, an inborn error of immunity
Immunodeficiency, centromeric instability, and facial anomalies jilungin dreaming tea (ICF) syndrome, a rare autosomal recessive disorder, manifests with hypoglobulinemia and chromosomal instability accompanied by DNA hypomethylation.Pathological variants in the DNMT3B, ZBTB24, CDCA7, or HELLS genes underlie its etiology.Activated lymphocytes from